Friday, August 15, 2014

What is the role of fibrin in blood clotting?

Fibrin is a protein substance that is synthesized by the liver and plays an essential role in blood clotting.


Fibrin is formed through polymerization and is the component of the clot, that stops the bleeding.


The doctor may recommend the fibrin test if the patient shows deficiencies in coagulation or if suffering from massive bleeding.


The normal values of fibrin in the blood: 200-400 mg per 100 ml of blood.


Decrease of fibrin levels mentioned above can cause bleeding in patients who have liver disease.


Fibrin increases, over values mentioned above, appear in acute infectious diseases and especially in rheumatic fever.


Relatively high levels of fibrin are occurring during pregnancy.

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